PANEL MODERATORS & PARTICIPANTS
The detailed information for the 2006 HBS Healthcare Club Conference panel moderators and participants will be updated as information becomes available. 

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Medical Device Innovation, Moderator
Leon Amariglio
Co-Founder
Rhythmia Medical, inc
Leon co-founded the company in 2004. Prior to Rhythmia, Leon spent three years as the director of business development for Ceragon Networks (NASDAQ: CRNT), a manufacturer of high speed fixed wireless equipment, where he also served as interim CFO, led the company's NASDAQ IPO, ran investor relations and served as a member of the executive team. Prior to Ceragon, Leon spent three years with the technology investment banking team at Deutsche Bank Alex Brown, where he oversaw multiple financing and M&A transactions on behalf of global technology companies. Leon speaks six languages, and holds an MBA from Harvard Business School, and a B.A. and M.Eng in Mechanical Engineering and Material Science from the University of Cambridge, UK. Leon is leading the business development efforts at Rhythmia.

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Commercializing Stem Cell Research, Panelist
Marc Beer
Chief Executive Officer
ViaCell
Mr. Beer joined ViaCell as President and Chief Executive Officer in April 2000. Prior to ViaCell, he was a senior manager at Genzyme for four years, most recently serving in the role of Vice President, Global Marketing for Genzyme Corporation. Mr. Beer has more than 15 years' experience in profit and loss management, and research and development program management in therapeutic, surgical and in vitro diagnostic systems businesses. Mr. Beer has served as a member of the board of directors of RenaMed Biologics, Inc., formerly Nephros Therapeutics, Inc., a private company, since 2001. Mr. Beer has a B.S. from Miami University (Ohio).

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Life Cycle of a Biotech Company, Panelist
Joshua Boger, Ph.D.
President and CEO
Vertex Pharmaceuticals
Dr. Joshua Boger is the founder, President and Chief Executive Officer of Vertex Pharmaceuticals Incorporated. He has been the Company's CEO since 1992, and also served in the additional role of Chairman of the Board from

1997 until 2006. Dr. Boger served as Vertex's Chief Scientific Officer from

1989 until May 1992, and has been a Director since Vertex's inception. Prior to founding Vertex in 1989, Dr. Boger held the position of Senior Director of Basic Chemistry at Merck Sharp & Dohme Research Laboratories in Rahway, New Jersey, where he headed both the Department of Medicinal Chemistry of Immunology & Inflammation and the Departmentof Biophysical Chemistry. Dr.

Boger holds a B.A. in chemistry and philosophy from Wesleyan University and M.S. and Ph.D. degrees in chemistry from Harvard University

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Commercializing Stem Cell Research, Panelist¡¡
Bruce Booth
Principal
Atlas Ventures¡¡
Bruce Booth joined Atlas Venture in 2005 as a Principal on the Life Sciences team.

Prior to Atlas Venture, Bruce was a Principal at Caxton Health Holdings L.L.C., a healthcare-focused investment firm. He focused on the firm's private equity activities, ranging from early stage venture capital through late stage buyouts. Prior to joining Caxton Health, he was an Associate Principal at McKinsey & Company, a global strategic management consulting firm, where he focused on R&D productivity, corporate strategy, and business development issues for several major biopharmaceutical companies. While at McKinsey, he also co-led the Firm's international scholars recruiting efforts.

Bruce sits on the Board of Zafgen and works closely with Atlas Venture portfolio companies ARCA Discovery, Archemix, Dynogen, Prestwick and NxStageMedical.

As a British Marshall Scholar, Bruce earned a Doctorate in Molecular Immunology from the Oxford University's Nuffield Department of Medicine and the Weatherall Institute of Molecular Medicine. His research focused on viral and tumor immune surveillance, and how the immune system responds to intracellular pathogenesis. During his graduate studies at Oxford, he also received the Overseas Research Fellowship and served as junior dean of Trinity College. Prior to graduate studies, he worked on President Clinton's Domestic Policy Council in the National Office of AIDS Policy. He received a Bachelor of Science degree with highest honors in Biochemistry from the Pennsylvania State University, where he was an Evan Pugh Scholar. 

Emerging Revolutions in Bioscience, Panelist
Abbie Celniker, Ph. D.
Global Head, Program Office
Novarits Institutes for Biomedical Research
Abbie Celniker, Ph.D is the Global Head of the Program Office for the Novartis Institutes for Biomedical Research (NIBR). In this role, Dr. Celniker is responsible for the global integration and oversight of the Novartis Discovery Portfolio. In her last role at Millennium Pharmaceuticals, Dr. Celniker led the pipeline portfolio review committee and headed Development Project Management and Pharmaceutical Sciences. Previously, Dr. Celniker headed the biotherapeutics, and the research and development strategy and operation functions at Millennium. Prior to Millennium, Dr. Celniker was at the Genetic Institute division of Wyeth Ayerst Research, where she was assistant vice president for predevelopment and biopharmaceutical core technologies. She has previously held positions at Genentech Inc. and the University of Arizona Cancer Center. Dr. Celniker has a bachelor's degree in biology from the University of California at San Diego and earned her Ph.D. in molecular biology at the University of Arizona.

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Life Cycle of a Biotech Company, Panelist
John Dee
President and CEO
Hypnion Inc.
John F. Dee has served as President, Chief Executive Officer and Director of Hypnion, Inc. since July 2000.

Prior to Hypnion, Mr. Dee spent a significant portion of his professional career with McKinsey & Co., Inc., where he conducted performance-improvement and strategic growth initiatives for major corporations. After leaving McKinsey in 1997, he conducted ¡°turnarounds¡± of biotechnology companies as an acting Chief Executive Officer.

Under Mr. Dee¡¯s leadership, Hypnion has raised approximately $80 million in venture capital, has built an outstanding scientific team and technology platform, and is now positioned to compete and win in the sleep disorder marketplace over the long term.

In non-profit pursuits, Mr. Dee led a group of Bay Area economists and business leaders in a diagnostic and public policy review of the San Francisco Bay Area¡¯s economic performance. He also advised the Pacific Presidio Center, a non-profit environmental group, on the potential redesign of the Presidio army base into a world environment center

Mr. Dee holds an M.S. in Engineering from Stanford University and an M.B.A. from Harvard University.

Life After the MBA in Healthcare, Panelist
Bill Fruhan
Senior Manager, Marketing Science Group
Boston Scientific
Bill has spent the majority of his career in the medical field, working for companies in the biotechnology (Genzyme), pharmaceutical (Eli Lilly), and medical device (Boston Scientific) areas.

Bill initially joined Boston Scientific in marketing to help launch TAXUS, the company's billion dollar drug-eluting stent. He has since become a Senior Manager within the Marketing Science group, an

internal strategy and market research team.

Bill has a BA from Middlebury College and an MBA from Harvard Business School.

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Life Cycle of a Biotech Company, Panelist
Nicholas Galakatos, Ph.D.
Managing Director
Clarus Ventures
Nicholas Galakatos, Ph.D., has over 21 years of direct industry and investment experience within the healthcare sector. Dr. Galakatos has been a General Partner in a healthcare venture capital firm since 2000. From 1997-2000, Dr. Galakatos was Vice President of New Business at Millennium Pharmaceuticals (NASDAQ: MLNM) where he co-founded Millennium Predictive Medicine and TransForm Pharmaceuticals. Prior to Millennium he was an associate at Venrock Associates focusing on early stage biotechnology investments. Prior to Venrock he was Head of Molecular Biology Research at Novartis (formerly Ciba).

Companies in which Dr. Galakatos has recently led financings include Affymax (spinout from GSK), Aveo, Critical Therapeutics (NASDAQ:CRTX), Hypnion, Portola (spinout from Millennium), Syrrx (acquired by Takeda), and TransForm (acquired by J&J).

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The Emerging Revolution in Biosciences, Panelist
Jeremy P. Goldberg
Managing Director, Corporate Development
Endo Pharmaceuticals ¡¡
Jeremy P. Goldberg joined Endo in 2003 as Managing Director, Corporate Development.  In this position, Mr. Goldberg is responsible for Endo¡¯s overall corporate development activities including structuring, negotiating and closing transactions such as the acquisition of companies, technology, products and product lines. Under his direction, Endo has formed strategic alliances with a number of companies for the rights to marketed and development products across several therapeutic areas, including:

  • Noven Pharmaceuticals, Inc. -- Generic transdermal patches
  • Vernalis plc -- Frova® for the acute treatment of migraine headaches in adults
  • Orexo AB -- Rapinyl for breakthrough cancer pain
  • DURECT Corporation -- Transdermal sufentanil patch for moderate-to-severe chronic pain
  • ProEthic Pharmaceuticals, Inc.¡ªTopical ketoprofen patch for acute pain associated with soft-tissue injuries
  • ZARS Pharma, Inc. ¨C Topical local anesthetic patch for superficial venous access.

Mr. Goldberg has more than 20 years of experience, much of which was focused on investing and business development activities in the pharmaceutical and healthcare industries. Most recently, he was a founding partner with ProQuest Investments, the first cancer-focused venture capital fund, where he and partners raised more than $250 million to acquire positions in biotechnology, specialty pharmaceutical, and medical device companies. In the mid-1990s, he was the founding CEO of Versicor, Inc., (n/k/a Vicuron, which was sold to Pfizer for $1.9B), a spin-out of Sepracor, Inc. He also  held marketing and business development assignments at Becton Dickinson and SmithKline Beckman.

Mr. Goldberg is a graduate of Harvard College and Harvard Business School. He serves on visiting committees at the Dana Farber Cancer Institute and the UCSF (University of California, San Francisco) Cancer Center.   

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Emerging Trends in Healthcare Delivery, Panelist¡¡
Allan Goroll, MD
Professor of Medicine
Harvard Medical School
Allan Goroll, MD, is Professor of Medicine at Harvard Medical School and a leading medical educator, author, advocate, and senior primary care internist at Massachusetts General Hospital in Boston. He is the Editor of Primary Care Medicine, 5th edition and has served as President of the Massachusetts Medical Society, Governor of the American College of Physicians - Massachusetts Chapter, and founding Chair of the Massachusetts eHealth Collaborative.

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Life Cycle of a Biotech Company, Moderator
Robert F. Higgins
Managing General Partner
Highland Capital
Bob has more than twenty years of experience in venture capital and has served as a director of many public and private companies. He is a former director of the National Venture Capital Association and President of the New England Venture Capital Association.

Bob has been an investor in many successful healthcare services, medical technology and information technology companies. Some of the services companies he has backed are Community Health Systems (NYSE: CYH), Mariner Health Group (IPO/acquired), New England Critical Care (IPO/acquired), Renal Treatment Centers (IPO/acquired) and U.S. Labs. Bob's medical technology investments include AVEO Pharmaceuticals, Conor Medsystems (Nasdaq: CONR), Helicos BioSciences, Magen BioSciences, Mitotix (Neuer Market: GPC Biotech AG), Origin Medsystems (acquired), PerSeptive Biosystems (IPO/acquired), Pervasis Therapeutics and PRAECIS PHARMACEUTICALS (Nasdaq: PRCS). In addition, Bob has also served on the boards of SmartBargains, Staples.com and WordWave (acquired by Merrill Corporation).

Before co-founding Highland, Bob was a general partner at a Boston-based venture capital partnership. Immediately prior to entering venture capital, he spent four years as the Executive Director of the John A. Hartford Foundation. He also was the Chief Executive of the Clark Foundation and the Burden Foundation. Bob is a former Assistant to the U.S. Secretary of Commerce and an Assistant to the head of the international division of the U.S. Treasury.

Bob holds a BA from Harvard College and an MBA from Harvard Business School

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Medical Device Innovation, Moderator¡¡
Ken Hutt
Principal
Deloitte Consulting
Ken Hutt has 20 years industry and consulting experience working with life sciences, high-tech and telecom companies. Dr Hutt is a leader in our Strategy Practice with a particular focus on R&D, developing new businesses and profitably commercializing high technology products. He has worked with a number of leading medical device companies on product and market entry strategies. Over the past several years he has been instrumental in establishing our Innovation and Growth practice; this practice takes the core ideas from disruption theory and applies them within a big company environment. The aim is to make growth a much more repeatable and predictable process.

Dr. Hutt moved from Industry to join Deloitte Consulting in 1998. He is a native of Scotland and graduated from the University of St. Andrews. He subsequently completed his Ph.D. in Physics from the University of Cambridge. Dr Hutt lives in Atlanta. ¡¡
Medical Device Innovation, Panelist
¡¡ David D. Israeli, MD
Marketing Director
Medtronic, Inc.

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David Israeli is currently the Director of Marketing for Heart Failure Diagnostics & Monitoring within the Cardiac Rhythm & Disease Management business unit of Medtronic, Inc. His responsibilities include the preparation for launch of a novel implantable diagnostic device, enabling clinicians to monitor heart failure patients remotely and provide early warning for pending clinical deterioration. Prior to this role, Dr. Israeli served as a Senior Associate within Medtronic¡¯s Corporate Development group, focusing on M&A activities and placing minority investments in early-stage companies. While still in Israel, David led a team within a start-up company developing an electronic patient record for obstetrical wards. Dr. Israeli earned a B.Med.Sc. (Summa Cum Laude) and a MD from the Hebrew University of Jerusalem as well as a MBA from the Harvard Business School.

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Emerging Trends in Healthcare Delivery, Panelist
Jon Kingsdale
Executive Director
Commonwealth Health Insurance Connector Authority

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The Commonwealth Health Insurance Connector Authority is an independent authority established under Massachusetts¡¯ landmark health reform legislation of 2006, to promote coverage of the uninsured. As the founding E.D., Mr. Kingsdale works closely with a representative Board of Directors to develop key elements of the policy. Dr. Kingsdale is responsible for policy development, government relations and consumer-directed health products.

Previously, he served as Senior Vice President of planning and development, where he was responsible for strategic planning and led major product initiatives including the development of various new HMO benefits for the group market (including tiered-network HMO and POS plans), New England¡¯s largest Medicare + Choice HMO, and Liberty by Tufts Health Plan, powered by Destiny Health, our consumer-driven health plan, which launched in the fall of 2003.

Dr. Kingsdale joined Tufts Health Plan in 1986, after 10 years in health care financing and management. His work experience included executive roles in strategic planning and reimbursement at Blue Cross Blue Shield of Massachusetts, policy issues consulting in Washington, D.C., and reporting for Forbes Magazine.
Dr. Kingsdale received a doctorate in economic history from the University of Michigan and a B.A. in history from the University of Pennsylvania. He has taught at the Harvard School of Public Health and the Boston University School of Public Health, and currently teaches at the Tufts University School of Medicine. He is President of the Board of Directors of Ethos, a non-profit agency enhancing home care services for seniors in Boston.
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Emerging Revolutions in Bioscience, Moderator
Bill Kridel
Managing Director and Founder
Ferghana Partners
Bill is responsible for new business development and for all types of transactions across all of the industry segments covered by the firm as well as participating in the evaluation of science, technology and clinical development aspects of clients, counterparties and competitor companies.

In 1991-1992, Bill was a Managing Director of Barclays de Zoete Wedd Limited (BZW) with responsibility for corporate finance and M&A advisory services in a number of countries and a number of sectors including pharmaceuticals, chemicals and oil & gas. Following the sale of his investment banking company, The Kridel Group, to Peers & Company in 1988, Bill ran its European operations from the Paris office of this investment banking affiliate of the Long Term Credit Bank of Japan until early 1991. From 1977-1988 his firm, The Kridel Group, with offices in the US and Europe, specialized in mergers and acquisitions, divestitures and equity private placements. From 1971-1977, Bill was a Vice President in the International Corporate Finance Department at Baring Bros. & Co in London and Paris. From 1970-1971, Bill worked in the International Finance and Acquisition group at Banque Paribas in Paris.

Following his honors graduations from Choate School, Yale University (BA) and Columbia Law School (JD), and attendance at other institutions for business and chemical engineering degrees, Bill qualified as an attorney in the United States, successfully gaining the license to practice before many bars, including New York State, Patent Court and the US Supreme Court, and practiced (M&A/financings) for a while on Wall Street at Shearman & Sterling. Bill is a regular attendee, Chairman and well-respected presenter, at many leading industry-specific conferences (biotech, pharma and chemicals), usually covering M&A and Corporate Partnering topics.
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Emerging Trends in Healthcare Delivery, Panelist
¡¡ Robert Mandel, MD, MBA
Vice President of Healthcare Services
Blue Cross Blue Shield of Massachusetts (BCBSMA)

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Dr. Robert Mandel, MD, MBA and Vice President of Healthcare Services, recently returned to Blue Cross Blue Shield of Massachusetts (BCBSMA) from the Massachusetts eHealth Collaborative (MAeHC), where he served as COO for a year. Prior to this, he was Vice President of eHealth at BCBSMA managing the eHealth Program with a significant focus on the eRx Collaborative and piloting medical decision support applications and other technologies that offer the potential of improving the quality and efficiency of care delivery. In addition, Dr. Mandel spent three years as Vice President of Provider Enrollment and Services where he led many of the organization¡¯s administration simplification initiatives.

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Commercializing Stem Cell Research, Panelist¡¡
Daniel R. Marshak, Ph.D.
Vice President & Chief Scientific Officer
PerkinElmer, Inc
Daniel R. Marshak, Ph.D. is Vice President and Chief Scientific Officer for PerkinElmer, Inc. (NYSE:PKI). Dr. Marshak is responsible for setting the strategic direction of PerkinElmer's research and development functions, and helping drive its growth strategies in the emerging areas of personalized medicine and predictive diagnostics. Most recently, Dr. Marshak was Vice President & Chief Technology Officer, Biotechnology, for Cambrex Corporation (NYSE:CBM), setting strategy in biosciences and participating in corporate and commercial activities. Dr. Marshak joined Cambrex in 2000, and through 2001 led R&D worldwide for the Bioscience sector. Concurrently, Dr. Marshak also holds an appointment as Adjunct Associate Professor at The Johns Hopkins University School of Medicine, Baltimore, Maryland.

Previously (1994-2000), Dr. Marshak was Senior Vice President and Chief Scientific Officer for Osiris Therapeutics, Inc., a U.S. biotechnology company developing adult stem cell products for the regeneration of diseased or damaged tissues. He was previously (1986-1995) Senior Staff Investigator at the Cold Spring Harbor Laboratory, Long Island, New York, where he and the members of his laboratory conducted research in signal transduction, cellular growth control, and differentiation. Dr. Marshak was concurrently (1987-1994) Assistant Professor, School of Medicine, State University of New York at Stony Brook, where he taught graduate biochemistry.

Dr. Marshak received his B.A. from Harvard University, Cambridge, Massachusetts, in Biochemistry & Molecular Biology, and his Ph.D. from The Rockefeller University, New York City, in Biochemistry & Cell Biology. He did postdoctoral research in Pharmacology at Vanderbilt University School of Medicine, Nashville, Tennessee, and at the National Institutes of Health, Bethesda, Maryland. Dr. Marshak has received several awards for scientific and academic achievements. He is also an inventor on six issued U.S. patents.

Dr. Marshak has extensive research experience in the growth control of human cells. Dr. Marshak is author of more than 100 scientific publications, including one textbook, and he has been editor of five monographs. The most recent monograph, Stem Cell Biology, was published in 2001 by The Cold Spring Harbor Laboratory Press.

Medical Device Innovation, Panelist
Terry McGuire
Managing Partner
Polaris Venture Partners
Terry McGuire is a co-founder and managing general partner of Polaris Venture Partners based in the Boston office. Terry focuses on life sciences investments. Prior to starting Polaris, Terry spent seven years at Burr, Egan, Deleage & Co. investing in early stage medical and information technology companies. Terry began his career in venture capital at Golder, Thoma and Cressey in Chicago. Terry has co-founded three companies: Inspire Pharmaceuticals (ISPH); AIR (Advanced Inhalation Research, Inc.), acquired by Alkermes (ALKS); and MicroCHIPS. Terry currently serves on the boards of the Thayer School of Engineering, Dartmouth College; the Private Equity and Entrepreneurship Center at the Amos Tuck School, Dartmouth College; the National Venture Capital Association; the MIT Center for Cancer Research; the Advisory Board of Harvard Business School¡¯s Healthcare Initiative; the Whitehead Institute for Biomedical Research; and the Advisory Board of the Arthur Rock Center for Entrepreneurship, Harvard Business School. He is a former board member of the Massachusetts Biotechnology Council and MassMEDIC. Terry holds an MBA from Harvard Business School, an MS in engineering from The Thayer School at Dartmouth College, and a BS in physics and economics from Hobart College.
Life After the MBA in Healthcare, Panelist
Ian McLean
MBA Associate, Pharmaceuticals
Bristol Myers Squibb Company

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Ian McLean currently works in Bristol Myers Squibb¡¯s Medical Imaging division in their MBA Associate position. He reports to the VP: In-line Marketing, having recently completed a year rotation in Field Sales. Prior to HBS, Ian worked at Maxxam Analytics Inc, Canada¡¯s largest private analytical laboratory in multiple business functions.  He has an undergrad Biology degree from Wilfrid Laurier University, Waterloo, ON, Canada.

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Life after the MBA in Healthcare, Moderator¡¡
Rahul Mehendale
Manager
Deloitte Consulting
Rahul Mehendale is a Manager in Deloitte's Strategy and Operations practice. At Deloitte, he is helping develop a disruptive innovation and growth focused management strategy consulting practice leveraging Disruption Theory. Rahul helped design and take to market a disruptive opportunity identification process to guide innovation activity and Multi-Generational Product Planning. He is currently developing applications of disruptive innovation to financial service, healthcare, pharmaceuticals, and technology industries.

Prior to joining Deloitte in November 2003, he worked as an independent consultant advising the executive board of a 400 person start-up, in the automotive services space for Cummins Inc. in India. He has worked with the Net Solutions Group at Novell Inc. in Boston, leading a joint go-to-market with Intel Inc. and setting up a technology showcase laboratory for Novell Inc. Rahul is a co-founder of a successful retail security solutions providing company, StopLift, Inc., that leverages facial recognition technologies and outsourcing to prevent shoplifting. He also worked at Cummins Inc. in Columbus IN as an Assembly and Test Engineer from March 1999 to August 2001, participating in a corporate strategy project to decide on the independence of Cummins Inc., leading supply chain management initiatives across the USA, UK, Mexico, India and China, heading new manufacturing systems design and implementation, and leading new product introduction programs for the fuel systems business.

Rahul attended Harvard Business School, where he graduated MBA with Distinction in 2003. Additionally he has an MS in Manufacturing Systems Engineering from the University of Wisconsin-Madison, and a BE in Mechanical Engineering from the University of Pune, India.

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Life after the MBA in Healthcare, Panelist
Sarah Mullen
Vice President of Operations
Caritas St. Elizabeth's Medical Center
Sarah Mullen Rich is currently Vice President of Operations for Caritas St. Elizabeth's Medical Center in Boston. She oversees a variety of hospital departments and has responsibility for surgical program development and growth. Prior to joining St. E's, Sarah worked for Tenet Healthcare. After

joining Tenet's Leadership Development Program, Sarah worked at St. Vincent Hospital in Worcester, MA and then accepted a position at Tenet's Corporate office where she led the development of the company's Balanced Scorecard. Before attending HBS, Sarah was an investment banker at JP Morgan and worked

for private equity firm JLL. As a private equity associate, she evaluated many healthcare investment opportunities, and helped form IASIS Healthcare.

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The Emerging Revolution in Biosciences, Panelist
Manuel A. Navia
Executive-in-Residence
Oxford Bioscience Partners
Dr. Navia is currently an Executive-in-Residence at Oxford Bioscience Partners, a large healthcare focused venture capital partnership. He is also a consultant for a number of pharmaceutical companies in the Boston area. Earlier, he was Executive Vice President for Research at Essential Therapeutics, (NASD: ETRX), which was formed through the merger of Microcide Pharmaceuticals and the Althexis Company in 2001. Dr. Navia was a founder of Althexis and served as its President and Chief Executive Officer. He is an expert in the field of X-ray crystallography, and has focused his career on the application of structural biology to the design and development of novel therapeutic agents through the application of structure-based drug design. Until recently, Dr. Navia was also a member of the Advisory Council of the Office of AIDS Research at the National Institutes of Health, where he chaired the Therapeutic Research Working Group.

In 1980, Dr. Navia established the first industrial macromolecular structure laboratory in the U.S., at Merck & Co., Inc., where he worked on the structures of human neutrophil elastase (a drug target for emphysema) and of carbonic anhydrase (for ocular hypertension and glaucoma). From 1989 to 1997, Dr. Navia was Vice-President and Senior Scientist at Vertex Pharmaceuticals in Cambridge, MA, where his interests in structure-based drug design were focused on studies of the FK506 binding protein and calcineurin (for immunosuppression), IL-1b converting enzyme (for inflammation), and HIV-1 protease (for AIDS), among other projects. In addition, Dr. Navia invented the cross-linked enzyme crystal (CLEC) catalyst technology that is currently under development across a broad front by Altus Biologics, a company that he co-founded.

Dr. Navia holds a B.A. degree in Physics from New York University (1967), an M.S. in Biophysics from the University of Chicago (1969) and a Ph.D. in Biophysics from the University of Chicago (1974).

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Life After the MBA in Healthcare, Panelist
Sara Nayeem
Associate, Healthcare Investment Banking
Merrill Lynch
Sara Nayeem joined Merrill Lynch¡¯s Global Healthcare Group in 2006. Within the Global Healthcare Group, she works in the life sciences and healthcare services spaces. Sara worked as an Analyst at Morgan Stanley between 1999 and 2001 in the Global Power and Utility Group, where she worked on mergers and acquisitions and corporate finance projects. Prior to joining Merrill Lynch, Sara was at Yale University, where she obtained her MD (cum laude) and MBA degrees (Yale MBA Scholar). Sara obtained her undergraduate degree (magna cum laude) in biological sciences from Harvard University. Sara has conducted and presented research on mammalian cardiovascular development and on quality of life in age-related macular degeneration.
The Emerging Revolution in Biosciences, Panelist
Steve Projan
VP and Head of Department of Biological Technologies
Wyeth¡¡
Steve Projan joined Wyeth in 1993 as a group leader in anti-infectives research.

Dr. Projan became an Associate Director, Bacterial Genetics in January of 1997 and then Director, Antibacterial Research in June of 1998.  In May of 2003 Dr. Projan was appointed Assistant Vice President, Protein Technologies and in September 2004 Dr. Projan was promoted to Vice President and Head of the newly created Dept. of Biological Technologies.  At Wyeth Dr. Projan was the Biology Team Co-Leader of the Glycylcycline Discovery Team that produced tigecycline, which had been approved in the U.S. for the treatment of bacterial infections including those caused by multidrug resistant strains.

Prior to joining Wyeth Dr. Projan was an Associate at the Public Health Research Institute, continuing his studies on plasmid replication, antibiotic resistance and staphylococcal virulence though 1994.  In 1987 Dr. Projan also became a senior scientist and then group leader at Applied Microbiology, Inc. (at that time an in house Biotech company at the Public Health Research Institute) working on antimicrobial enzymes and bacteriocins (small antibacterial proteins).  There he developed a novel, protein-based method for the prevention of bovine mastitis that was marketed to the dairy industry and he also developed a novel protein expression system for the production of an anti-staphylococcal protein that has entered clinical trials. 

Dr. Projan attended M.I.T. for his undergraduate education, receiving an S.B. degree
(in the Life Sciences and Nutrition & Food Science) in 1974.  He then graduated with a Ph.D. from Columbia University in 1980 (also receiving M.A. and M.Phil. degrees from that institution), spending 1977 -1980 at the University of Utah.  Dr. Projan¡¯s graduate work was done with Jim Wechsler and they were successful in developing the first in vitro system that initiated chromosomal DNA replication from the E. coli origin of replication.  Dr. Projan then became a postdoctoral fellow with Richard Novick at the Public Health Research Institute in New York City studying plasmid replication and virulence in Staphylococcus aureus. 

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Commercializing Stem Cell Research, Panelist¡¡
Brock Reeve
Harvard Stem Cell Institute
Brock Reeve, a graduate of Yale and the Harvard Business School, is Executive Director of the Harvard Stem Cell Institute. Brock comes to Harvard from the commercial sector with extensive experience in both management consulting and operations for technology-based companies, with a focus on life sciences. Brock¡¯s business career started with the Boston Consulting Group. Most recently, Brock was COO and Managing Director of Life Science Insights, an IDC company, a consulting and market research firm specializing in information technology in life sciences. LSI worked with biopharma companies helping them understand how best to leverage information technology at all stages of the business value chain and with life science software and hardware companies helping them understand their market and associated opportunities. Prior to LSI, Brock was an Associate Partner in the Pharmaceutical and Life Sciences practice in IBM¡¯s Business Consulting Services group, working with biotech and pharmaceutical clients on issues ranging from R&D portfolios to operations strategies. Brock also has had hands-on operational responsibility in product management and marketing roles in software start-ups as well as additional experience in IT and the healthcare/life science market as the Healthcare Practice Director at Viant Corp. and a Principal at SRI Consulting.
Commercializing Stem Cell Research, Panelist
¡¡ William Sahlman
Professor of Business Administration; Senior Dean for External Relations
Harvard Business School ¡¡
William Sahlman is the Dimitri V. d'Arbeloff - Class of 1955 Professor of Business Administration at Harvard Business School. The d'Arbeloff Chair was established in 1986 to support teaching and research on the entrepreneurial process. The Chair honors the late Dimitri d'Arbeloff (HBS '55), whose entrepreneurial skills helped make Millipore Corporation a world leader in its industry.

Mr. Sahlman received an A.B. degree in Economics from Princeton University, an M.B.A. from Harvard University, and a Ph.D. in Business Economics, also from Harvard.

His research focuses on the investment and financing decisions made in entrepreneurial ventures at all stages in their development. Mr. Sahlman was co-chair of the Entrepreneurship and Service Management Unit from 1999 to 2002. From 1991 to 1999, he was Senior Associate Dean, Director of Publishing Activities, and chairman of the board for Harvard Business School Publishing Corporation. From 1990 to 1991, he was chairman of the Harvard University Advisory Committee on Shareholder Responsibility. He is a member of the board of directors of several private companies.

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Medical Device Innovation, Panelist¡¡
Aaron Sandoski
Managing Director
Norwich Ventures

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Aaron Sandoski is the Managing Director of Norwich Ventures, a seed and early-stage venture capital firm specializing in the medical device industry.  Mr. Sandoski has a hands-on approach to investing and he is actively involved with the firm¡¯s portfolio companies.  Currently, he serves on the boards of Syncro Medical Innovations and Genisent International. As the Managing Director, Mr. Sandoski is also responsible for the day-to-day activities of Norwich.

Prior to founding Norwich Ventures, Mr. Sandoski worked at DEKA R&D, the engineering think tank of Dean Kamen, where he helped develop partnerships and formulate business plans for emerging technologies. He has also worked in start-up operations where he helped launch a subsidiary of Express Scripts and helped launch a venture-backed payments company. Both companies were acquired in transactions totaling over $500 million. Mr. Sandoski began his career as a consultant at McKinsey & Company, where he advised healthcare clients ranging from leading medical device companies to a rural hospital system. 

Mr. Sandoski takes an active interest in business and economic decision-making as well as teaching.  He is currently writing a book with a former colleague on the topic of business decision-making that will be published in 2007 by the Random House imprint, Crown Business.  In the past, he has taught introductory micro- and macro-economics at Harvard University as a Teaching Fellow where he won the Allyn Young Teaching Prize.

Mr. Sandoski earned an MBA from Harvard Business School and graduated summa cum laude from Dartmouth College with a double A.B. in Chemistry and Economics.  He lives in the Boston area with his wife and son.

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Life Cycle of a Biotech Company,Panelist
Edward Scolnick, M.D.
Director of the Psychiatry Initiative Broad Institute
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Edward Scolnick works closely with principal investigator Pamela Sklar towards identifying risk genes for bipolar disorder and schizophrenia. From 1982-2003, Ed served as president of Merck Research Laboratories; executive vice president for science and technology at Merck & Company, Inc; executive director and vice president in the department of virus and cell biology and senior vice president for basic research at Merck Research Laboratories.
Prior to Merck, Ed worked at the National Cancer Institute and the National Heart Institute. Ed was elected to the National Academy of Sciences in 1984 and to the American Academy of Arts and Sciences in 1993. He became a member of the Institute of Medicine in 1996 and served on the Board of Directors of Merck & Co., Inc. from 1997 to 2002. He recently was selected as Regents' Lecturer, University of California at Berkeley, Frank H.T. Rhodes Class of '56 University Professor at Cornell University, and appointed to the Board of Visitors at the University of Pittsburgh School of Medicine.
He currently serves on the board of directors for Millipore Corporation; Renovis, Inc.; and TransForm Pharmaceuticals, Inc.; and on the Medical and Scientific Advisory Board for MPM Capital. He was a member of the FDA Science Board from 2000 to 2002.
Ed holds an A.B. from Harvard College and an M.D. from Harvard University Medical School.

Life After the MBA in Healthcare, Panelist¡¡
Rachel Sha
Business Development Associate, Biotechnology
Genzyme

Rachel Sha currently works in Business Development at Genzyme in the Biosurgery unit. She has evaluated opportunities ranging from products in early stage development to commercialized products in orthopedics and general surgery. She was a Global Marketing and Sales intern at Novartis. Prior to HBS, Rachel worked at Accenture where she was a manager in their Electronics & High Tech consulting group. She holds a BS in Chemistry from MIT.

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Medical Device Innovation, Panelist¡¡¡¡
Dr. John W. Sheets
Vice President and Chief Technical Officer
Ethicon, a Johnson & Johnson company

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As the WWVP and Chief Technical Officer for ETHICON, one of the largest Johnson & Johnson medical device franchises, Dr. John Sheets is responsible for the oversight of all technology for the company's multi-billion dollar surgical products, cardiovascular, women's health and wound management business units. Prior to his career with Johnson & Johnson, Dr. Sheets spent nearly a decade as Vice President, Surgical /IOL & Therapeutics R&D with Alcon Laboratories, the world's largest specialty ophthalmic company. Dr. Sheets received his Ph.D. in Materials Science and Engineering from the University of Florida and completed the Harvard Business School's Program for Management Development.

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Commercializing Stem Cell Research, Moderator
¡¡ Debora Spar
Professor, Senior Associate Dean, Director of Research
Harvard Business School¡¡
Debora Spar is the Spangler Family Professor at Harvard Business School, where she works on issues of business-government relations and the political environment of international commerce.

Dr. Spar's current research focuses on issues of foreign trade and investment, examining how firms compete in foreign markets and how government policies shape and constrain their options. She is particularly interested in information-based industries such as media, entertainment, and biotechnology. Her current research examines the politics of reproductive science, analyzing how the "baby business" has developed and how commerce, politics and technology are likely to interact in and affect this market. Other projects examine the political drivers of foreign direct investment and the impact of investment on human rights and labor standards. At Harvard, Dr. Spar is Senior Associate Dean, Director of Research and teaches courses on the politics of international business, comparative capitalism, and economic development. She is also Chair of Making Markets Work, an executive education program devoted to public and private sector leaders in Africa, and teaches and consults for a number of multinational corporations, government agencies, and non-governmental organizations.

Dr. Spar is the author of numerous publications in academic and public policy journals. Her latest book, The Baby Business was published by Harvard Business School Press in January 2006. She is also author of Ruling the Waves: Cycles of Discovery, Chaos, and Wealth from the Compass to the Internet and The Cooperative Edge: The Internal Politics of International Cartels, and co-author with Raymond Vernon of Beyond Globalism: Remaking American Foreign Economic Policy

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Emerging Trends in Healthcare Delivery, Panelist¡¡
Andrew P. Vaz
Principal
Deloitte Consulting
Andrew Vaz is National Director of Health Provider practice responsible for all services and solutions. Andrew is also responsible for the development of all intellectual capital and methodologies to support the transformation of provider healthcare organizations. He has over 20 years of experience in the healthcare industry. Prior roles include Managing Director of the Canadian and Northeast Healthcare practices at Ernst & Young. Andrew has also led the Healthcare Emerging Technology practice, as well as the Health High Growth practice for Cap Gemini Ernst & Young.

Andrew¡¯s consulting career has spanned strategy and business planning, business/technology enabled transformation and the management of change. His client base has included large multi-national pharmaceutical, biotechnology and medical supply organizations, reference laboratories, large academic health sciences centers, academic organizations, integrated delivery systems, provider organizations across the continuum of care, managed care companies, and numerous health technology organizations. He has successfully led the development of emerging technology strategies for world class health organizations, enterprise wide business transformation and re-engineering of academic medical centers in Canada and the US, facilitated numerous mergers and joint ventures and developed leading edge strategies for organizations in the provider, payer and life sciences sectors.

Some of Andrew¡¯s clients include Partners Healthcare, Memorial Sloan Kettering, Northshore Long Island Jewish Health System, University of Pittsburgh Medical Center, Cleveland Clinic, and Hospital Corporation of America.

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The Emerging Revolution in Biosciences, Panelist
Frederic J. Vinick , Ph.D.
Senior Vice President of Drug Discovery
Genzyme Corporation

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Fred Vinick was educated at Williams College ( B.A. in Chemistry , 1969 ) , Yale University ( Ph.D. in Organic Chemistry with Professor Harry Wasserman , 1973 ) and Columbia University ( two years of postdoctoral research in the laboratories of Prof. Gilbert Stork ).

Dr. Vinick was a member of the medicinal chemistry department at Ciba Geigy Corporation from 1974-1978. He then moved to Pfizer Central Research where over the course of a sixteen-year career, he worked in the areas of exploratory process research , CNS medicinal chemistry and exploratory medicinal chemistry. As the founder and director of Pfizer's New Leads group in 1986 he helped establish high throughput screening, compound library acquisitions and high speed chemical synthesis methods. While at Pfizer, Dr. Vinick contributed to patents and publications on selective phosphodiesterase inhibitors, nonpeptide substance P antagonists and bradykinin antagonists. In 1994 he assumed the position of Vice President, Drug Discovery at Genzyme Corporation. He is currently Senior Vice President of Drug Discovery. Dr. Vinick continues to have a major interest in highly efficient approaches to drug discovery which manage the inherent risk of a low probability of ultimate success

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¡¡ Saturday,

December 2, 2006
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